{"id":1084,"date":"2023-11-06T08:00:00","date_gmt":"2023-11-06T08:00:00","guid":{"rendered":"https:\/\/exka.com\/?p=1084"},"modified":"2025-10-01T13:42:51","modified_gmt":"2025-10-01T13:42:51","slug":"cold-ethanol-extraction-of-cannabinoids-and-terpenes-from-cannabis-using-response-surface-methodology-optimization-and-comparative-study","status":"publish","type":"post","link":"https:\/\/exka.com\/en\/cold-ethanol-extraction-of-cannabinoids-and-terpenes-from-cannabis-using-response-surface-methodology-optimization-and-comparative-study\/","title":{"rendered":"Cold ethanol extraction of cannabinoids and terpenes from cannabis using response surface methodology: optimization and comparative study"},"content":{"rendered":"
\n
\n \n <\/span>\n\n \n
\n
\n

Cold ethanol extraction of cannabinoids and terpenes from cannabis using response surface methodology: optimization and comparative study<\/h1>\n

 <\/p>\n \n <\/div>\n <\/div>\n <\/div>\n<\/section>\n\n\n\n

Main Lines<\/h2>\n\n\n\n
\n
\n
\n \n
\n
\n\n

\n Optimum conditions <\/h3>\n \n

Using response surface methodology, the optimum conditions predicted at different extraction temperatures were a cannabis\/ethanol ratio of 1:15 and an extraction time of 10 minutes.<\/p>\n \n <\/article>\n

\n\n

\n Temperature variations <\/h3>\n \n

Extracting cannabis at different temperatures leads to variations in the concentration of tetrahydrocannabinolic acid (THCA) and terpenes, with lower temperatures leading to greater changes.<\/p>\n \n <\/article>\n

\n\n

\n Conclusion <\/h3>\n \n

Cold ethanol extraction has been studied to increase the extraction yield and concentration of cannabinoids and terpenes at different temperatures. Predictive models were developed and showed a strong correlation with experimental values. Optimal conditions for cannabis oil extraction have been predicted. More research is needed to reduce the operational costs of the cannabis industry.<\/p>\n \n <\/article>\n <\/div>\n <\/div>\n <\/div>\n<\/section>\n\n\n\n

<\/div>\n\n\n\n
\n
\n
\"\"<\/figure>\n<\/div>\n\n\n\n
\n
\n

Extracting secondary compounds from cannabis presents a number of challenges.<\/h2>\n\n\n\n

Efficient extraction of cannabis biomass can increase yield while reducing costs and minimizing waste. Cold ethanol extraction was evaluated to maximize yields and concentrations of cannabinoids and terpenes at different temperatures.<\/p>\n\n\n\n

\n
Read Research Paper<\/strong><\/a><\/div>\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div>\n\n\n\n
<\/div>\n\n\n\n
\n
\n
\"\"<\/figure>\n<\/div>\n\n\n\n
\n
\n


For me, this study is important because it enabled me to evaluate different cold ethanol extraction conditions to optimize extraction yield and the concentration of cannabinoids and terpenes in cannabis oil. The results showed that temperatures of -20\u00b0C and -40\u00b0C were more effective than room temperature, and predictive models were developed to obtain reproducible results.<\/em><\/em><\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Main Lines Extracting secondary compounds from cannabis presents a number of challenges. Efficient extraction of cannabis biomass can increase yield while reducing costs and minimizing waste. Cold ethanol extraction was evaluated to maximize yields and concentrations of cannabinoids and terpenes at different temperatures. For me, this study is important because it enabled me to evaluate […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[89,88],"tags":[],"class_list":["post-1084","post","type-post","status-publish","format-standard","hentry","category-articles","category-research"],"acf":[],"_links":{"self":[{"href":"https:\/\/exka.com\/en\/wp-json\/wp\/v2\/posts\/1084","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/exka.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/exka.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/exka.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/exka.com\/en\/wp-json\/wp\/v2\/comments?post=1084"}],"version-history":[{"count":5,"href":"https:\/\/exka.com\/en\/wp-json\/wp\/v2\/posts\/1084\/revisions"}],"predecessor-version":[{"id":1960,"href":"https:\/\/exka.com\/en\/wp-json\/wp\/v2\/posts\/1084\/revisions\/1960"}],"wp:attachment":[{"href":"https:\/\/exka.com\/en\/wp-json\/wp\/v2\/media?parent=1084"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/exka.com\/en\/wp-json\/wp\/v2\/categories?post=1084"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/exka.com\/en\/wp-json\/wp\/v2\/tags?post=1084"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}